Cingal® Injection Therapy
If you’re living with the pain, swelling or stiffness of knee osteoarthritis, Cingal® may offer the effective, non-surgical solution you’ve been looking for. Combining two trusted treatments – Steroid Injection Therapy and Hyaluronic Acid Injection Therapy, into a single injection. Cingal delivers both rapid and long-lasting relief — helping you move more comfortably and stay active.
What is Cingal®?
Cingal® is a powerful, dual-action injection therapy designed to relieve knee pain caused by osteoarthritis. It uniquely combines:
- Corticosteroid (Triamcinolone Hexacetonide): to reduce inflammation and provide rapid relief within days.
- Hyaluronic Acid (HA): a natural joint lubricant, formulated here in a highly purified, cross-linked form for long-lasting cushioning and support.
Cingal® is the first and only CE-marked therapy to combine these two treatments in one injection, making it an ideal option for patients seeking convenience, speed, and sustained results.
Why Choose Cingal®?
- Fast relief — noticeable reduction in pain often within the first week
- Long-lasting effects — up to 6 months of joint pain relief with one injection
- One simple appointment — performed in-clinic with no need for anaesthesia
- Proven safety — both HA and corticosteroids have decades of successful clinical use
- Delay or avoid surgery — ideal for those looking to postpone joint replacement
How Does Cingal® Work?
Osteoarthritis causes a breakdown in the quality and quantity of hyaluronic acid in the joint — the substance that helps your joint fluid stay thick, elastic, and shock-absorbing. At the same time, inflammation builds up inside the joint, triggering pain and stiffness.
Cingal® addresses both problems at once:
- The hyaluronic acid restores lubrication and cushioning within the joint, improving mobility and reducing friction.
- The corticosteroid calms inflammation, helping relieve pain quickly and reduce swelling.
Together, these components support better joint function — and better quality of life.
What to Expect During and After Treatment
The Procedure
Cingal® is administered as a single injection directly into the knee joint. It takes just a few minutes and can be done during a routine clinic visit. No general anaesthesia is required.
After the Injection
You may feel slight swelling or tenderness around the joint for a day or two. It’s best to avoid intense activity for 48 hours, but you can usually resume light daily tasks immediately.
When Will I Feel Relief?
Most patients notice relief within a few days thanks to the corticosteroid. The HA component builds up over the following weeks, supporting ongoing comfort and joint movement.
How Long Will It Last?
Clinical studies show pain relief may last up to 6 months from a single injection.
When to use Cignal?
Cingal is particularly suitable for individuals with mild to moderate osteoarthritis of the knee who:
- Are no longer responding to over-the-counter pain relief
- Want to remain active without resorting to surgery
- Prefer a one-visit treatment with fast, noticeable benefits
- Cingal is suitable for patients managing multiple joint pain for example hips, shoulders, or knees.
How is Cingal different from standard joint injections?
Unlike standard HA or cortisone injections given separately, Cingal combines both in one injection — giving you immediate and sustained pain relief.
Is it safe?
Both components in Cingal (HA and corticosteroids) are clinically proven and have been used safely for decades. Side effects are generally mild and short-lived.
Can I have more than one injection?
Yes. If Cingal works well for you, it can be repeated after approximately six months, depending on your condition and clinician advice.
What joints can be treated?
Cingal is CE-mark approved for knee osteoarthritis, but the principles of viscosupplementation can be discussed for other joints such as hips or shoulders, based on your needs.
Where can I learn more about Cingal Injection Therapy?
If you want more detail about outcome measures, clinical studies, etc., please see the Cingal website.
Cingal® is a registered trademark, and the Cingal® logo and images copyright of Anika Therapeutics, Inc. .